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Biotechnology

Course Description

The Biotechnology Graduate Program requires each student to take 6 core courses. These courses are designed to give students the academic foundation necessary to understand the theory behind a wide variety of techniques used in today’s biotechnology laboratory. The required labs that accompany each core course give students opportunities to gain valuable training with the equipment and techniques actually used in the biotech industry. In addition to the core courses, each student chooses two electives to gain specialized knowledge in more specific areas of interest.

CORE CURRICULUM

Fall

BTC 559 Advanced Biotechniques: Advanced techniques in the isolation, purification and manipulation of nucleic acids and proteins.
BTC 563 Molecular Biochemistry: Application of molecular genetics to transcription control mechanisms; gene expression, molecular cloning, and applications to biotechnology

Spring

BTC 557 Advanced Metabolism: Theoretical aspects of enzymatic reaction mechanisms; mechanisms of inhibitors and fermentation technology. Laboratory training will involve the preparation of a particular enzyme or other protein product by small pilot fermentation technology.
BTC 555 Proteins and Nucleic Acids: Molecular basis for eukaryotic inheritance; structure and function; chromosomal organization; DNA replication and repair, transcription and translation; the genetic code, regulation of gene expression, genetic differentiation; genetic manipulation.

Summer

BTC 558 Biophysical Chemistry: Instrumental analysis of proteins, nucleic acids, carbohydrates, and lipids. Methods to include ultracentrifugation; gradient separation of proteins and nucleic acids; UV/Visible spectroscopy; electrochemistry of cytochromes; X-ray diffraction of proteins and nucleic acids; and HPLC of proteins.
BTC 560 Advanced Biochemistry: Current advanced biochemical concepts focusing on research topics including the role of actin, myosin I, Myosin II in cyto kinesis. Emphasis in protein chemistry on membrane topology and structural analysis of P450 mixed function oxidases. Other topics will include the role of complement in the functions of the immune system, surfactant protein gene expression in pulmonary alveoli, tumor suppressor proteins and cancer, and RNA protein interactions.

This schedule of core courses is repeated each year. Students can enter the program at the beginning of any semester.

LIST OF ELECTIVES

BTC 561 Biotechnology I: The topics covered in this course will include gel electrophoresis for analysis of proteins and nucleic acids; radiochemistry; DNA and RNA synthesis, isolation, cloning, and sequencing; RFLP; expression of proteins; and restriction enzyme analysis. Fall.
BTC 562 Biotechnology II: This course covers protein chemistry, immunology, the techniques of preparing tissue cultures, physical biochemistry, receptors and receptor assays, microscopy, computational biotechnology, molecular modeling, and the biometric analysis of data at an advanced level. Spring.
BTC 503 Introduction to Biotechnology: Hands-on experience with fundamental techniques of the biotechnology industry. The course presents topics of biotechnology and discusses the scientific and social issues. Participants will explore textbooks, journals, lab kits and other resources available to teachers.
BTC 576 Critical Reading I&II: Advanced courses designed to help students develop critical reading and anlytical thinking skills. Students read and evaluate the methods and results presented in published papers. The class is presented in a discussion format that is lead by a team of scientists from a variety of interests. Fall and Spring.
BTC 575 Scientific Laboratory Concepts: A presentation of fundamental mathematical, algebraic, analytical and calculus concepts used in the scientific laboratory. Important information for laboratory bench work and for data analysis. Summer I
CHE 471 Forensic DNA Analysis: A study of forensic DNA analysis. The study will include background information about collecting evidence, analysis techniques and laboratory procedures. The study will include information about interpreting the results, the significance of the results and the regulation of quality control. Spring.

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University of Texas Health Center at Tyler

Biotechnology

Course Description